Research Article

NFKB1 Gene Mutant Was Associated with Prognosis of Coronary Artery Disease and Exacerbated Endothelial Mitochondrial Fission and Dysfunction

Figure 4

Mitochondria were more sensitive to high-glucose/palmitate damage in NFKB1 DD-mutant cells. (a, b) Representative confocal photomicrographs stained with MitoSOX Red and mPTP. (c, d) Mean fluorescent intensities of MitoSOX and mPTP per cell. HUVECs were treated with 25 mM glucose and 250 μM palmitic acid (PA) for 3 hours. Data represents the of at least three independent cell culture preparations (more than 10 visual fields per group). and .