Research Article

NFKB1 Gene Mutant Was Associated with Prognosis of Coronary Artery Disease and Exacerbated Endothelial Mitochondrial Fission and Dysfunction

Table 2

MACCE and all-cause mortality events among CAD patients carrying different genotypes of NFKB1 gene rs28362491.

II ()ID ()DD () value

Non-MACCE ()173 (33.0)278 (53.1)73 (13.9)—
MACCE ()40 (22.6)89 (50.3)48 (27.1)<0.001
All-cause mortality ()13 (27.1)24 (50.0)11 (22.9)0.226
Cardiac mortality ()10 (32.3)13 (41.9)8 (25.8)0.172
Noncardiac mortality ()3 (17.6)11 (64.7)3 (17.6)0.412
Nonfatal AMI ()5 (22.7)11 (50.0)6 (27.3)0.190
Unplanned revascularization ()11 (21.2)24 (46.2)17 (32.7)0.001
Malignant arrhythmia ()1 (14.3)5 (71.4)1 (14.3)0.555
Cardiac failure ()8 (22.0)18 (50.0)10 (27.8)0.060
Stroke ()2 (16.7)7 (58.3)3 (25.0)0.361

MACCE: major adverse cardiac and cerebrovascular event; AMI: acute myocardial infarction.