Research Article

Erythropoietin Resistance Development in Hemodialysis Patients: The Role of Oxidative Stress

Table 5

General data of the patients, categorized by type of EPO administered and presence of EPO resistance.

General dataShort-acting EPOLong-acting EPO
NonresistantResistantNonresistantResistant

Age (years)60.00 (12.50)60.00 (11.00)
HD treatment length (years)2.50 (7.16)3.67 (4.35)1.42 (2.54)3.84 (6.73)
SBP (mmHg)130.00 (20.00)130.00 (7.50)130.00 (20.00)125.00 (30.00)
DBP (mmHg)80.00 (10.00)80.00 (10.00)80.00 (5.00)80.00 (10.00)
MBP (mmHg)96.67 (13.33)96.67 (9.17)96.67 (6.67)93.33 (16.67)
BW (kg)70.00 (15.00)66.42 (10.63)
IDWG (kg)2.00 (1.50)2.42 (1.00)
UR (mL/h)500.00 (375.00)625.00 (250.00)
UR (mL/kg/h)
RD (mL/24 h)500.00 (1000.00)350.00 (1250.00)1000.00 (1200)500 (1000)
Qavf (mL/min)750.00 (750.00)800.00 (637.50)750.00 (990.00)600.00 (675.00)
PKD
CG (, %)3 (7.69)1 (8.33)2 (9.52)2 (8.33)
HN (, %)13 (33.33)5 (41.67)4 (19.05)6 (25.00)
DN (N, %)7 (17.95)3 (25.00)4 (19.05)4 (16.67)
ON (, %)4 (10.26)0 (0.00)0 (0.00)2 (8.33)
CN (, %)11 (28.21)3 (25.00)3 (14.29)7 (29.17)
PK (, %)1 (2.56)0 (0.00)8 (38.10)3 (12.50)

Values are expressed as means ± SD for normally distributed data, or as median (interquartile range) where data were not normally distributed. HD, hemodialysis; SBP, systolic blood pressure; DBP, diastolic blood pressure; MBP, mean blood pressure; BW, body weight; IDWG, interdialytic weight gain; UR, ultrafiltration ratio; RD, residual diuresis; Qavf, arteriovenous fistula flow; Kt/V, hemodialysis adequacy index; spKt/V, single-pool hemodialysis adequacy index; URR, urea reduction ratio; PKD, primary kidney disease; CG, chronic glomerulonephritis; HN, hypertensive nephropathy; DN, diabetic nephropathy; ON, obstructive nephropathy, CN, chronic nephropathy; PK, polycystic kidney disease.