Research Article
IL-22 Protects against Biliary Ischemia-Reperfusion Injury after Liver Transplantation via Activating STAT3 and Reducing Apoptosis and Oxidative Stress Levels In Vitro and In Vivo
Figure 6
IL-22 plays a protective role by activating STAT3 in vitro. (a) Expression of STAT3 and p-STAT3 proteins in HIBEpiCs treated with IL-22 at different times. (b) Expression of STAT3 and p-STAT3 proteins after using 10 μM and 20 μM concentrations of STAT3 inhibitor stattic. (c) The cell cycle was detected after stattic (10 μM) treatment, and there was no significant difference in the proportion of cells in the 4N phase compared with the CoCl2 group. Data are shown as . . NS: no statistical difference.
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