Research Article

IL-22 Protects against Biliary Ischemia-Reperfusion Injury after Liver Transplantation via Activating STAT3 and Reducing Apoptosis and Oxidative Stress Levels In Vitro and In Vivo

Figure 7

Effects of stattic treatment on apoptosis, ROS, and mitochondrial membrane potential in each group. (a) Apoptosis levels of HIBEpiCs in each group. There was no significant difference in apoptosis rate between stattic treatment and CoCl2 group. (b) After stattic treatment, the expression of antiapoptotic proteins decreased, and the expression of proapoptotic proteins increased compared with CoCl2+IL-22 group. (c) After stattic treatment, mitochondrial membrane potential was not significantly different from the CoCl2 group. (d) After stattic treatment, the level of ROS was not significantly different from the CoCl2 group. Data are shown as . . NS: no statistical difference; MFI: mean fluorescence intensity.
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