[Retracted] Exploring the Temporal Correlation of Sarcopenia with Bone Mineral Density and the Effects of Osteoblast-Derived Exosomes on Myoblasts through an Oxidative Stress–Related Gene

Figure 10

Schematic diagram of molecular mechanisms. The cross-lagged models indicated that LDL-C positively predicted appendicular lean mass. WBTOT BMD, LS BMD, and PELV BMD temporally and positively predicted appendicular lean mass, while appendicular lean mass in turn temporally and positively predicted WBTOT BMD, LS BMD, and PELV BMD. Moreover, this study revealed that femur osteoblast–derived exosomal lncRNA TUG1 and skull osteoblast–derived exosomal DANCR exerted opposite effects on myoblast differentiation through regulating the transcription of Myog gene by modifying the binding of Myf5 to the Myog gene promoter via affecting the nuclear translocation of Myf5 as transporters.