Changes of Functional, Morphological, and Inflammatory Reactions in Spontaneous Peripheral Nerve Reinnervation after Thermal Injury

Figure 4

Nerve pathological changes assessed via light and electron microscopy after slight, moderate, and severe thermal injury. (a) Getting histologic results via light microscopy, the black box in the severe group indicates characteristics of coagulation and homogenization (H&E staining, 200x). (b, c) Comparison of the pathological changes of axons and myelin sheaths (TEM). White triangles indicate the hyperpigmentation of axonal fibers. Black arrows indicate the loose myelin sheaths with reduced anchoring particles. Black triangle indicates macrophages adjacent to the myelin sheath. White arrows indicate bubbles in myelin sheaths. TEM: transmission electron microscopy.