Research Article

P16INK4a Regulates ROS-Related Autophagy and CDK4/6-Mediated Proliferation: A New Target of Myocardial Regeneration Therapy

Figure 8

Research pattern diagram. P16INK4a can not only regulate ROS metabolism to induce autophagy but also can affect the proliferation of cardiomyocytes by inhibiting CDK4/6, ultimately affecting the myocardial regeneration and repair after injury.