Research Article

[Retracted] Genetic Analysis Reveals Different Mechanisms of IL-5 Involved in the Development of CAD in a Chinese Han Population

Table 2

Allelic association analysis between IL5 and CAD.

PopulationSNP alleleMAFOR (95% CI)
CaseControlCaseControl

Discoveryrs2057687T6677290.0870.1340.7930.0350.68 (0.47-0.97)
rs78546665T6196920.1480.1660.2590.1970.1730.81 (0.59-1.10)
rs2069812G7427450.2850.3130.2240.0990.5190.93 (0.73-1.07)

Validationrs2057687T99310230.1230.1190.0500.6900.6611.05 (0.84-1.31)
rs78546665T9079720.1820.1650.2010.1610.1571.16 (0.95-1.41)
rs2069812G103910170.3020.3010.0200.9530.8600.99 (0.84-1.15)

Combinedrs2057687T166017520.1080.1250.1020.0300.2250.89 (0.74-1.07)
rs78546665T152616640.1680.1660.8060.7600.6741.04 (0.88-1.22)
rs2069812G178117620.2950.3060.0110.3070.3360.94 (0.83-1.07)

SNP: single nucleotide polymorphism; CAD: coronary artery disease; MAF: minor allele frequency; : observed value; , value adjusted by the covariates; age, sex, BMI, hypertension, diabetes mellitus, smoking history, Tch, TG, HDL-c, and LDL-c were adjusted; OR: odds ratio after adjustment; : value from the Hardy–Weinberg equilibrium tests.