[Retracted] Genetic Analysis Reveals Different Mechanisms of IL-5 Involved in the Development of CAD in a Chinese Han Population
Table 5
Allelic and genotypic association analyses of IL5 with CAD in gender subgroups.
SNP allele
Model
Male
Female
OR (95% CI)
OR (95% CI)
rs2057687T
ALLE
0.007
0.025
0.77 (0.62-0.97)
0.703
0.264
1.20 (0.87-1.65)
DOM
0.014
0.027
0.76 (0.59-0.97)
0.729
0.279
1.22 (0.85-1.73)
REC
0.079
0.373
0.68 (0.29-1.60)
0.820
0.630
1.33 (0.42-4.22)
ADD
0.024
0.025
0.77 (0.62-0.97)
0.932
0.269
1.20 (0.87-1.64)
rs78546665T
ALLE
0.619
0.281
1.12 (0.91-1.38)
0.983
0.490
0.91 (0.69-1.20)
DOM
0.798
0.385
1.11 (0.88-1.40)
0.974
0.663
0.93 (0.67-1.29)
REC
0.376
0.290
1.46 (0.73-2.91)
0.986
0.376
0.70 (0.31-1.56)
ADD
0.675
0.278
1.12 (0.91-1.38)
0.999
0.502
0.91 (0.69-1.20)
rs2069812G
ALLE
0.040
0.016
0.82 (0.70-0.97)
0.378
0.132
1.18 (0.95-1.45)
DOM
0.108
0.081
0.83 (0.68-1.02)
0.470
0.137
1.23 (0.94-1.62)
REC
0.073
0.021
0.67 (0.48-0.94)
0.497
0.454
1.18 (0.76-1.83)
ADD
0.112
0.018
0.83 (0.71-0.97)
0.695
0.149
1.16 (0.95-1.42)
: observed value; : value adjusted by the covariates; OR: odds ratio after adjustment; ADD: additive mode, rs2057687_TT/CT/CC, rs78546665_TT/GT/GG, and rs2069812_GG/AG/AA; DOM: dominant mode, rs2057687_TT+CT/CC, rs78546665_TT+GT/GG, and rs2069812_GG+AG/AA; REC: recessive model, rs2057687_TT/CT+CC, rs78546665_TT/GT+GG, and rs2069812_GG/AG+AA.
