RNF7 Facilitated the Tumorigenesis of Pancreatic Cancer by Activating PI3K/Akt Signaling Pathway

Figure 4

RNF7 promotes cell growth by activating the PI3K/Akt signaling pathway in PC cells. (a, b) GO enrichment analysis of similar genes in the BP, MF, and CC categories and KEGG signaling pathways (KEGG analysis) enriched with the similar genes. (c) Western blot analysis of the activity of PI3K/Akt signaling in PC cellular lineage (SW1990 and PANC-1) when RNF7 was upregulated. (d) Western blot analysis of the activity of PI3K/Akt signaling in PC cellular lineage (SW1990 and PANC-1) when RNF7 was downregulated.

(a)

(b)

(c)

(d)