RNF7 Facilitated the Tumorigenesis of Pancreatic Cancer by Activating PI3K/Akt Signaling Pathway

<div>RNF7overexpression accelerated tumor growth in vivo. (a) Xenograft tumors were removed from Lv-RNF7 or Lv-NC groups. (b, c) Tumor volume and weight in Lv-RNF7 or Lv-NC groups were measured and calculated. (d) Immunohistochemical staining for Ki-67, PCNA, phospho-Akt, and phospho-mTOR in xenografts (scar bar: 50 <i>μ</i>m). (e) qRT-PCR was used to detect the expression levels of central members of PI3K/Akt signaling in each group. 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Oxidative Medicine and Cellular Longevity

fig6

Figure 6

Figure 6: RNF7 Facilitated the Tumorigenesis of Pancreatic Cancer by Activating PI3K/Akt Signaling Pathway 