Aldehyde Dehydrogenase 2 Protects the Kidney from Ischemia–Reperfusion Injury by Suppressing the IκBα/NF-κB/IL-17C Pathway

Figure 3

ALDH2 deficiency resulted in increased phosphorylation of IκBα/NF-κB P65 and il-17C expression. (a) The expression of IL-17 family mRNA in the kidney was determined by real-time PCR. GAPDH was the standard. /group. (b) The western blot band of p-IκBα, IκBα, p-p65, p65, and IL-17C in kidney lysates. β-Actin was the standard. /group. (c)–(e) Western blot analysis for p-IκBα, IκBα, p-p65, p65, and IL-17C protein in kidney samples from each group. /group. Data are presented as the . n.s.: not significant. , , and by -test.

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