The Microbiota-Dependent Treatment of Wuzhuyu Decoction for Chronic Migraine Model Rat Associated with Anxiety-Depression Like Behavior

<div>The gut microbiota mediated the effects of WZYD improving hyperalgesia and anxiety-depression like behavior. (a) Facial mechanism withdraw threshold. (b) Paw hot withdraw threshold. (c–h) The open field test. (c) The route of representative rat of five groups. (d) Total distance. (e) Total rest time. (f) Number of traveling inner. (g) Inner distance (ID%). 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Oxidative Medicine and Cellular Longevity

fig1

Figure 1

Figure 1: The Microbiota-Dependent Treatment of Wuzhuyu Decoction for Chronic Migraine Model Rat Associated with Anxiety-Depression Like Behavior 