Research Article
Microbiota from Exercise Mice Counteracts High-Fat High-Cholesterol Diet-Induced Cognitive Impairment in C57BL/6 Mice
Table 1
The relative abundance of the top 10 gut bacterial genera at the phylum, class, order, family, and genus levels (%) (mean ± SEM).
| Level | CON | FMTSED | FMTEX |
| Phylum | | | | Actinobacteria | 0.0678 ± 0.0200 | 0.0111 ± 0.0033 | 0.0225 ± 0.0091 | Cyanobacteria | 0.0000 ± 0.0000 | 0.0003 ± 0.0001 | 0.0001 ± 0.0000 | Firmicutes | 0.4230 ± 0.0410 | 0.2351 ± 0.0394 | 0.3255 ± 0.0449 | Proteobacteria | 0.0178 ± 0.0098 | 0.0790 ± 0.0051 | 0.0916 ± 0.0094 | TM7 | 0.0000 ± 0.0000 | 0.0007 ± 0.0005 | 0.0001 ± 0.0000 | Tenericutes | 0.0015 ± 0.0004 | 0.0002 ± 0.0001 | 0.0003 ± 0.0002 | Verrucomicrobia | 0.0456 ± 0.0107 | 0.2872 ± 0.0522 | 0.1446 ± 0.0271# | Class | | | | Verrucomicrobia | 0.0456 ± 0.0107 | 0.2872 ± 0.0522 | 0.1446 ± 0.0271# | Erysipelotrichi | 0.1010 ± 0.0189 | 0.0366 ± 0.0100 | 0.0836 ± 0.0241 | Deltaproteobacteria | 0.0173 ± 0.0100 | 0.0619 ± 0.0056 | 0.0620 ± 0.0068 | Coriobacteriia | 0.0506 ± 0.0185 | 0.0031 ± 0.0006 | 0.0036 ± 0.0009 | Gammaproteobacteria | 0.0004 ± 0.0001 | 0.0170 ± 0.0065 | 0.0294 ± 0.0037 | Actinobacteria | 0.0172 ± 0.0024 | 0.0080 ± 0.0032 | 0.0200 ± 0.0090 | Bacilli | 0.0233 ± 0.0015 | 0.0048 ± 0.0008 | 0.0104 ± 0.0003 | Order | | | | Verrucomicrobiales | 0.0456 ± 0.0107 | 0.2872 ± 0.0522 | 0.1446 ± 0.0271# | Erysipelotrichales | 0.1010 ± 0.0189 | 0.0366 ± 0.0100 | 0.0836 ± 0.0241 | Desulfovibrionales | 0.0173 ± 0.0100 | 0.0619 ± 0.0056 | 0.0620 ± 0.0068 | Coriobacteriales | 0.0506 ± 0.0185 | 0.0031 ± 0.0006 | 0.0036 ± 0.0009 | Enterobacteriales | 0.0004 ± 0.0001 | 0.0170 ± 0.0065 | 0.0294 ± 0.0037 | Bifidobacteriales | 0.0172 ± 0.0024 | 0.0080 ± 0.0032 | 0.0200 ± 0.0090 | Lactobacillales | 0.0233 ± 0.0015 | 0.0048 ± 0.0008 | 0.0104 ± 0.0003 | Family | | | | Verrucomicrobiaceae | 0.0456 ± 0.0107 | 0.2872 ± 0.0522 | 0.1446 ± 0.0271# | Erysipelotrichaceae | 0.1010 ± 0.0189 | 0.0366 ± 0.0100 | 0.0836 ± 0.0241 | Paraprevotellaceae | 0.0000 ± 0.0000 | 0.0735 ± 0.0146 | 0.0965 ± 0.0301 | Lachnospiraceae | 0.0417 ± 0.0060 | 0.0395 ± 0.0100 | 0.0590 ± 0.0051# | Desulfovibrionaceae | 0.0173 ± 0.0100 | 0.0619 ± 0.0056 | 0.0620 ± 0.0068 | Coriobacteriaceae | 0.0506 ± 0.0185 | 0.0031 ± 0.0006 | 0.0036 ± 0.0009 | Clostridiaceae | 0.0154 ± 0.0034 | 0.0055 ± 0.0015 | 0.0028 ± 0.0015# | Genus | | | | Akkermansia | 0.0456 ± 0.0107 | 0.2872 ± 0.0522 | 0.1446 ± 0.0271# | Prevotella | 0.0000 ± 0.0000 | 0.0735 ± 0.0146 | 0.0965 ± 0.0301 | Bacteroides | 0.0001 ± 0.0000 | 0.0205 ± 0.0068 | 0.0166 ± 0.0060 | Lactobacillus | 0.0218 ± 0.0013 | 0.0021 ± 0.0003 | 0.0071 ± 0.0023# | Desulfovibrio | 0.0173 ± 0.0098 | 0.0000 ± 0.0000 | 0.0000 ± 0.0000 |
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p <0.05 versus CON group by Mann–Whitney test. #p <0.05 versus FMTSED group by Mann–Whitney test. |