Single-Cell Sequencing Reveals Necroptosis-Related Prognostic Genes of Glioblastoma

Figure 5

Mutation landscape analysis related to NCPTS in TCGA GBM. (a) The difference of TMB between the high- and low-NCPS groups. (b) The difference of top mutation genes between the high- and low-NCPS groups. (c, d) Mutation landscape between the high- and low-NCPS groups of TCGA dataset. The top 20 mutation genes between the two groups are listed on the left side, and the percentage of each mutation is listed on the right side. The mutation incidence rate of top 3 genes PTEN, EGFR, and TTN in the high risk groups was 25% (17 of 68 samples), 24% (16 of 68 samples), and 19% (13of 68 samples) of GBM patients, while, in the low risk groups, the mutation incidence rate of TP53, EGFR, and TTN was 32% (22of 69 samples), 25% (17 of 69 samples), and 22% (15 of 69 samples).

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