Osthole Inhibits M1 Macrophage Polarization and Attenuates Osteolysis in a Mouse Skull Model

Figure 1

Effect of OST on the cell viability of the BMMs in the CCK-8 assay. (a) The proliferation and viability of the BMMs were assessed using the CCK-8 assay following incubation with indicated concentrations of OST for 24, 48, and 72 h. (, , ). (b) The half-inhibitory concentration of OST in the BMMs was 269.7 μM at 24 h, 141.2 μM at 48 h, and 100.5 μM at 72 h.

(a)

(b)