[Retracted] Active Ingredient Paeonol of Jijiu Huiyang Decoction Alleviates Isoproterenol-Induced Chronic Heart Failure via the GSK3A/PPARα Pathway

Figure 4

The effects of paeonol on the heart function of ISO-induced CHF mice. The (a) LVESD, (b) LVEDD, (c) LVPWD, (d) IVSD, (e) LVEF, and (f) LVFS were measured based on long-axis M-mode echocardiography. (g) The heart-to-body weight ratio of the mouse. (h) The ratio of the weight of the mouse’s heart to the length of the tibia. vs. Pae-50 group. ^##, ^###vs. CHF group. Pae: paeonol; ISO: isoproterenol; CHF: chronic heart failure; LVESD: left ventricular end-systolic diameter; LVEDD: left ventricular end-diastolic diameter; LVPWD: end-diastolic left ventricular posterior wall thickness; IVSD: interventricular septal thickness in diastole. LV fractional shortening (LVFS%) and LV ejection fraction (LVEF%) were recorded by two-dimensional M-mode echocardiography. TL: tibia length; BW: body weight; HW: heart weight.

(a)

(b)

(c)

(d)

(e)

(f)

(g)

(h)