A Multifunctional (-)-Meptazinol-Serotonin Hybrid Ameliorates Oxidative Stress-Associated Apoptotic Neuronal Death and Memory Deficits via Activating the Nrf2/Antioxidant Enzyme Pathway

Figure 5

Mep-S improves scopolamine-induced learning and memory dysfunction in mice. The escape latency to the platform (a), swimming tracks (b), and average swimming speeds (c) of mice during the 5-day training sessions. vs. control group; ^# and ^## vs. scopolamine-treated group. The proportions of swimming distance (d) and time (e) in the target quadrant and average swimming speeds (f) of mice during the probe trial on day 6. One-way ANOVA: , (distance); , (time); F(5, 54) = 0.17, (speeds). Data are expressed as the (). and .

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