Research Article
PINK1-Interacting Proteins: Proteomic Analysis of Overexpressed PINK1
Table 1
Potential interactors of PINK1.
| Swiss-Prot accession no. | Gene | Protein name | Subcellular localization | No. of unique peptides | Sequence coverage in % | Band on PAGE gel | Previous report of interaction |
| P42704 | LRPPRC | Leucine-rich PPR motif-containing protein | Mitochondrion | 2 | 1.8 | a | none | P07900 | HSP90A | Heat shock 90 kDa protein alpha | Cytoplasm | 27 | 28.5 | b | Weihofen et al. [19] | P08238 | HSP90B | Heat shock 90 kDa protein beta | Cytoplasm | 18 | 21.9 | b | Weihofen et al. [19] | P38646 | GRP75 | 75 kDa glucose-regulated protein/Mortalin | Mitochondrion, cytoplasm | 6 | 10.8 | c | none | P11021 | GRP78 | 78 kDa glucose-regulated protein | Endoplasmic reticulum | 15 | 28.7 | c | none | P08107 | HSPA1 | Heat shock 70 kDa protein 1 | Cytoplasm, organelles | 10 | 17.3 | c | none | P34931 | HSPA1L | Heat shock 70 kDa protein 1-like | Cytoplasm, organelles | 8 | 13.7 | c | none | P54652 | HSPA2 | Heat shock 70 kDa protein 2 | Cytoplasm, organelles | 4 | 7.2 | c | none | P11142 | HSPA8 | Heat shock 70 kDa protein 8 | Cytoplasm | 7 | 12.7 | c | none | P10809 | HSP60 | Heat shock 60 kDa protein | Mitochondrion | 7 | 16.2 | d | none | Q9BQE3 | TUBA1C | Tubulin alpha-1C chain | Microtubule | 2 | 5.3 | f | none | Q13748 | TUBA3C | Tubulin alpha-3C/D chain | Microtubule | 3 | 10.7 | f | none | Q16543 | CDC37 | Hsp90 cochaperone Cdc37 | Cytoplasm | 10 | 22.2 | g | Weihofen et al. [19] | P49411 | TUFM | Elongation factor Tu | Mitochondrion | 3 | 8.0 | g | none |
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