Dementia after DBS Surgery: A Case Report and Literature Review

Table 1

Neuropsychological test battery results.

Psychological test	Examination date
	10/2005	1/2006*	3/2006**	6/2006	11/2006	3/2007	7/2008
WAIS-R (IQ)	129	14 MMSE only	102	27 MMSE only	97	90
Mattis DRS (raw/maximum score)
Total score	144/144					116/144	84/144
Attention	37/37					35/37	31/37
Initiation	37/37					29/37	14/37
Construction	6/6					5/6	2/6
Conceptualization	39/39					30/39	26/39
Memory	25/25					17/25	11/25
WORD-LIST WMS III (raw/scaled score)
1st trial	5/12		3/7			2/6	2/6
Immediate recall	29/11		22/7			13/4	15/4
Delayed recall	4/11		4/11			1/8	0/6
Recognition	22/10		23/11			18/7	15/4
Verbal fluency tests (raw score)
Category (animal)	20		1	14	7	4	6
letter (N, K, P)	45		19	6	10	7	5
Rey-Osterrieth CFT (raw/T score)
Copy (raw)	36		33		32.5	28	4.5
Immediate recall	21/67		10/43		15/57	12.5/52	1.5/25
Delayed recall	18.5/62		13/49		13.5/54	9/43	failed
Recognition	29/49		20/49		21/56	20/50	14/20
Stroop test (raw/T score)
Word	98/45			97/45	103/47	93/43	56/24
Color	73/45			61/37	65/40	34/20	31/20
Word/color	49/54			33/38	39/44	25/30	failed
Interference (T score)	57			50	49	55	—
Tower of London (raw/maximum score)	33/36					8/36	failed
MADRS	4	24		9	5	3	8

*1/2006: very poor compliance—only screening; **3/2006: still poor compliance, but much better than during the previous examination in 1/2006; WAIS-R: Wechsler Adult Intelligence Scale—Revised; Mattis DRS: Mattis Dementia Rating Scale; WMS III: Wechsler Memory Scale III; Rey-Osterrieth CFT: Rey-Osterrieth Complex Figure Test; MADRS: Montgomery-Asberg Depression Rating Scale.