Adenosine A_𝟐A Receptor Antagonists Do Not Disrupt Rodent Prepulse Inhibition: An Improved Side Effect Profile in the Treatment of Parkinson's Disease

Figure 1

Efficacy of SCH 412348 (a), istradefylline (b), pramipexole (c), pergolide (d), ropinirole (e), and L-dopa (f) to reduce catalepsy induced with 1 mg/kg haloperidol in rats. Data represent mean time cataleptic ± SEM and were analyzed by one-way ANOVAs with Dunnett’s tests (*𝑃<0.05; **𝑃<0.01 versus vehicle + haloperidol treatment).

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