Altered Mitochondrial Respiration and Other Features of Mitochondrial Function in <i>Parkin</i>-Mutant Fibroblasts from Parkinson’s Disease Patients

<div>Parameters of respiratory control in patient-derived and control fibroblasts. Boxplots depict grouped patients (P) and control (Ct) values. (a) Basal mitochondrial OCR. (b) ATP-linked OCR. (c) OCR due to proton leak. (d) ATP coupling efficiency (percentage OCR due to ATP synthesis). (e) Maximum OCR. 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°, outlier; AU, arbitrary units; OCR, oxygen consumption rate.</div>

Parkinson’s Disease

fig2

Figure 2

Figure 2: Altered Mitochondrial Respiration and Other Features of Mitochondrial Function in <i>Parkin</i>-Mutant Fibroblasts from Parkinson’s Disease Patients 

Figure 2 | Altered Mitochondrial Respiration and Other Features of Mitochondrial Function in Parkin-Mutant Fibroblasts from Parkinson’s Disease Patients 