Mini Review: Anticholinergic Activity as a Behavioral Pathology of Lewy Body Disease and Proposal of the Concept of “Anticholinergic Spectrum Disorders”

<div>At the stage of ACh downregulation, corresponding to the late stage of LBD, the patient develops symptoms related to ACh downregulation, which is induced by the continuous and recurrent appearance of AA. These symptoms include memory disturbances and disorientation to time and place. AA: anticholinergic activity, ACh: acetylcholine, AD: Alzheimer’s disease, HPA axis: hypothalamic-pituitary-adrenal axis, and LBD: Lewy body disease.</div>

Parkinson’s Disease

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Figure 4: Mini Review: Anticholinergic Activity as a Behavioral Pathology of Lewy Body Disease and Proposal of the Concept of “Anticholinergic Spectrum Disorders” 

Figure 4 | Mini Review: Anticholinergic Activity as a Behavioral Pathology of Lewy Body Disease and Proposal of the Concept of “Anticholinergic Spectrum Disorders” 