Deletion of Herpud1 Enhances Heme Oxygenase-1 Expression in a Mouse Model of Parkinson’s Disease

Figure 4

Expression of stress-related genes in cultured astrocytes. Herpud1^+/+ and Herpud1^−/− mice-derived astrocytes were treated with MPP⁺ for 16 h, and, after cell lysis, protein samples (30 μg/sample) were subjected to western blotting for HO-1, GRP78, and GAPDH. Each value shown is the mean ± SD (), and the value derived from Herpud1^+/+ astrocytes without MPP⁺ treatment is designated as one. ; , compared to cells without MPP⁺ treatment.