Blood Plasma of Patients with Parkinson’s Disease Increases Alpha-Synuclein Aggregation and Neurotoxicity

Figure 7

Effects of NS and PD plasma on GCase, PP2A, and PLK2 activities and ceramide levels in neurons. ((a)–(d)) Neurons were treated for 14 d and GCase activity (a), ceramide levels (b), and PP2A (c) and PLK2 (d) activities in the cytosolic fraction were evaluated (/group; one-way ANOVA followed by Tukey’s multiple comparisons test). , versus control group; , versus α-syn + NS group.

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