Effect of a Traditional Chinese Herbal Medicine Formulation on Cell Survival and Apoptosis of MPP⁺-Treated MES 23.5 Dopaminergic Cells

Figure 2

Detection of ROS in MES23.5 cells using flow cytometric analysis. MES23.5 cells were treated with MPP⁺ (100 μM) for 24 hours, followed by the posttreatment of CRJ for another 24 hours. MPP⁺ (100 μM) increased the production of ROS in MES23.5 cells. Posttreatment of CRJ resulted in the decrease of ROS production in MPP⁺-treated MES23.5 cells. Fluorescence intensity of control group was set as 100%. Data were represented as mean ± SEM in three independent experiments. , MPP⁺-treated cells as compared to control. , CRJ + MPP⁺ groups as compared to MPP⁺-treated cells.

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