Research Article

Relationship between Lower Urinary Tract Dysfunction and Clinical Features in Chinese Parkinson’s Disease Patients

Table 1

Demographic and clinical characteristics of the enrolled PD patients and the univariate analysis between PD-OAB and PD-NOAB.

Enrolled PD patientsPD-OABPD-NOABt/χ2/Z

Number of patients10045 (45%)55 (55%)
Gender (male/female)55/4529/1626/292.9490.086
Age (years)65.97 ± 8.247 (range 48–85)69.36 ± 7.5363.20 ± 7.82−3.982<0.001
Age of onset (years)61.45 ± 8.361 (range 40–81)64.30 ± 7.8359.13 ± 8.12−3.2170.002
Disease duration (years)4 (2, 7) (range 0.25–20)4 (2, 7)3.5 (1, 6)−0.9840.325
Education (years)9 (9, 12) (range 0–20)9 (9, 12)10 (9, 12)−0.7740.439
LEDD (mg)350 (178.13, 562.50) (range 0–1425)337.5 (193.75, 668.75)375 (150, 525)−0.3470.728
Motor symptom
Hoehn–Yahr stage2 (2, 3) (range 1–5)2.5 (2, 3.5)2 (2, 2)−2.8510.004
MDS-UPDRS-III score35 (27, 47.75) (range 12–112)39 (28.5, 56)34 (24, 44)−2.0690.039
 Clinical subtype
  Tremor-dominant (yes/no)67/3330/1537/180.0040.949
  Akinetic/rigid-dominant (yes/no)44/5620/2524/310.0070.935
Nonmotor symptom
 Hyposmia (yes/no)39/6119/2620/350.3570.550
RBD (yes/no)58/4231/1427/283.9820.046
 Constipation (yes/no)72/2833/1239/160.0720.788
 Anxiety and depression (yes/no)55/4526/1929/260.2550.614
 Hallucination (yes/no)11/896/395/500.4550.536
 MMSE score28 (26, 29) (range 11–30)27 (25.5, 29)28 (26, 29)−1.4540.146
MoCA score24 (21.25, 27) (range 7–30)24 (20, 26)26 (22, 28)−2.7210.007
FAB score15 (14, 16) (range 6–18)14 (12, 15)16 (15, 17)−5.034<0.001

; the difference was statistically significant.