Neuroinflammation and Myelin Status in Alzheimer’s Disease, Parkinson’s Disease, and Normal Aging Brains: A Small Sample Study

Figure 2

Astrocytes and microglia in the striatal tissue sections using GFAP and Iba1 antibodies. (a) Representative images of activated astrocytes and microglia in white matter, gray matter, and striatum. The activated astrocytes showed enlarged cell bodies and enlongated fibers, while activated microglia showed meatball-like appearance with enlarged cell bodies and shortened processes. The scale bar represents 100 μm. (b, c) The quantitative analysis of the GFAP and Iba1 expression in white matter in the astrocytosis and the nonastrocytosis groups. The bars represent mean ± SEM. represents .

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