Novel Compound Heterozygous PRKN Variants in a Han-Chinese Family with Early-Onset Parkinson’s Disease

Figure 1

(a) Pedigree of the family with EOPD. The arrow indicates the proband. (b) DNA sequencing of the c.719C > A variant in the PRKN gene. (c) DNA sequencing of the c.815T > G variant in the PRKN gene. (d) Conservation analysis of the parkin p.T240 amino acid residue. (e) Conservation analysis of the parkin p.L272 amino acid residue.

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