Association of Motor and Cognitive Symptoms with Health-Related Quality of Life and Caregiver Burden in a German Cohort of Advanced Parkinson’s Disease Patients

Table 1

Patient (n = 124, 61 females) and caregiver (n = 78, 42 females) characteristics.

	Mean ± SD	Min	Max
PD patients
Age (years)	72.5 ± 9.1	40	89
Education	Low 1.8%
	Middle 61.4%
	High 36.8%
Disease duration (years)	14.1 ± 7.6	1	37
Hoehn and Yahr stage	3.5 ± 1.1	1	5
MDS-UPDRS total	115.0 ± 47.7	12	210
MDS-UPDRS part I	17.4 ± 8.4	1	39
MDS-UPDRS part II	25.2 ± 11.9	1	48
MDS-UPDRS part III	48.1 ± 21.8	3	96
MDS-UPDRS part IV	7.2 ± 5.6	0	20
PDQ-8	40.4% ± 18.0%	0%	81.3%
MoCA	20.4 ± 6.7	0	30
MoCA-EIS	5.6 ± 5.2	0	15
MoCA-VIS	3.8 ± 1.2	0	5
MoCA-AIS	12.0 ± 4.8	0	18
MoCA-OIS	5.3 ± 1.5	0	9
MoCA-MIS	5.8 ± 5.2	0	15
MoCA-LIS	4.6 ± 1.4	0	6
BDI	11.3 ± 6.9	0	31
Barthel index	70.6 ± 26.5	10	100
Caregivers
Age (years)	64.8 ± 11.0	19	84
Caregiving hours per day	5.9 ± 7.0	0	24
PDCB	36.5 ± 27.1	0	100
BDI	9.3 ± 6.3	0	26
SF-36 total	67.4 ± 19.0	21.9	96.3

BDI, Beck Depression Inventory; PDCB, Parkinson’s disease caregiver burden inventory; MDS-UPDRS, Movement Disorders Society-unified Parkinson’s disease rating scale; MoCA, Montreal cognitive assessment scale; EIS, executive index score; VIS, visual index score; AIS, attention index score; OIS, orientation index score; MIS, memory index score; LIS, language index score; PD, Parkinson’s disease; PDQ-8, Parkinson’s disease questionnaire 8; SF-36, short form 36 health survey; SD, standard deviation.