Can the Executive Control Network be Used to Diagnose Parkinson’s Disease and as an Efficacy Indicator of Deep Brain Stimulation?

Table 2

Comparisons of functional connectivity of the brain networks during CN, pre-PD, and post-PD.

Brain regions	Peak MNI coordinate			Peak T value	Cluster size (mm^3)
	x	y	z
CN > pre-PD
R inferior frontal gyrus	48	24	15	5.44	1269
L precuneus	−27	−51	36	4.79	4698
R precuneus	21	−66	36	6.18	5967
L inferior frontal gyrus	−57	6	39	5.29	2430
R middle frontal gyrus	36	9	42	5.26	2862
R postcentral gyrus	24	−45	51	5.58	1350
R inferior parietal lobule	36	−57	36	4.72	2727
L cerebellum posterior lobe	−30	−78	−45	5.09	1458
CN > post-PD
L cerebellum posterior lobe	−30	−78	−42	5.27	1107
R inferior frontal gyrus	45	18	18	4.11	918
L inferior frontal gyrus	−57	6	39	5.60	4509
L precuneus	−27	−51	36	5.13	1809
R middle frontal gyrus	33	3	39	4.08	1377
R inferior parietal lobule	39	−69	54	4.33	1080
Pre-PD < post-PD
Nr	—	—	—	—	—

Abbreviations: CN, controls; pre-PD, preoperation Parkinson’s disease; post-PD, postoperation Parkinson’s disease; ECN, executive control network; Nr, no statistically significant differences between brain regions.