CUB and Sushi Multiple Domains (CSMD1) Gene Polymorphisms and Susceptibilities to Idiopathic Parkinson’s Disease in Northern Chinese Han Population: A Case-Control Study
Table 6
Distribution of rs1983474 polymorphism in different subcomponent types.
rs1983474
Genotype
PD (%)
Control (%)
OR (95% CI)
Male
TT
77 (34.4)
77 (31.3)
—
—
TG
107 (47.8)
132 (53.7)
0.015
2.160 (1.162–4.016)
GG
40 (17.9)
37 (15.0)
0.674
1.126 (0.649–1.954)
T
261 (58.3)
286 (58.1)
—
—
G
187 (41.7)
206 (41.9)
0.968
1.005 (0.776–1.303)
Female
TT
57 (28.6)
75 (34.2)
—
—
TG
90 (45.2)
116 (53.0)
0.999
1.000 (0.640–1.563)
GG
52 (26.1)
28 (12.8)
0.003
0.418 (0.234–0.746)
G
194 (48.7)
172 (39.3)
—
—
T
204 (51.3)
266 (60.7)
0.006
1.471 (1.118–1.935)
EOPD
TT
15 (35.7)
38 (56.7)
—
—
TG
23 (54.8)
22 (32.8)
0.021
0.358 (0.150–0.855)
GG
4 (9.5)
7 (10.4)
0.677
0.739 (0.177–3.074)
T
53 (63.1)
98 (73.1)
—
—
G
31 (36.9)
36 (26.9)
0.118
0.628 (0.350–1.127)
LOPD
TT
119 (31.2)
114 (28.6)
—
—
TG
174 (45.7)
223 (56.0)
0.047
1.393 (1.004–1.934)
GG
88 (23.1)
61 (15.3)
0.042
0.643 (0.420–0.985)
T
412 (54.1)
451 (56.7)
—
—
G
350 (45.9)
345 (43.3)
0.304
0.900 (0.737–1.100)
EOPD: early-onset Parkinson’s disease; LOPD: late-onset Parkinson’s disease; OR: odds ratio; CI: confidence interval. was statistically significant, which is given in bold.
