CUB and Sushi Multiple Domains (CSMD1) Gene Polymorphisms and Susceptibilities to Idiopathic Parkinson’s Disease in Northern Chinese Han Population: A Case-Control Study

Table 7

Distributions of rs12681349 polymorphism different subcomponent types.

rs12681349	Genotype	PD (%)	Control (%)		OR (95% CI)
Male
	CC	163 (72.8)	187 (76.0)	—	—
	CT	54 (24.1)	54 (22.0)	0.549	0.876 (0.569–1.350)
	TT	7 (3.1)	5 (2.0)	0.447	0.635 (0.198–2.043)
	C	380 (84.4)	428 (87.0)	—	—
	T	68 (15.2)	64 (13.0)	0.339	0.836 (0.578–1.208)
Female
	CC	146 (67.6)	169 (77.2)	—	—
	CT	45 (20.8)	42 (19.2)	0.793	0.940 (0.589–1.498)
	TT	8 (11.6)	8 (3.7)	0.812	0.885 (0.324–2.419)
	C	337 (84.7)	380 (86.8)	—	—
	T	61 (15.3)	58 (13.2)	0.389	0.843 (0.572–1.243)
EOPD
	CC	31 (73.8)	58 (86.6)	—	—
	CT	10 (23.8)	8 (11.9)	0.483	0.710 (0.272–1.849)
	TT	1 (2.4)	1 (1.5)	0.569	0.436 (0.025–7.585)
	C	72 (85.7)	124 (92.5)	—	—
	T	12 (14.3)	10 (7.5)	0.104	0.484 (0.199–1.176)
LOPD
	CC	278 (73.0)	293 (73.6)	—	—
	CT	89 (23.4)	93 (23.4)	0.700	0.936 (0.669–1.310)
	TT	14 (3.7)	12 (3.0)	0.588	0.804 (0.365–1.769)
	C	645 (84.6)	679 (85.3)	—	—
	T	117 (15.4)	117 (14.7)	0.717	0.950 (0.719–1.254)

EOPD: early-onset Parkinson’s disease; LOPD: late-onset Parkinson’s disease; OR: odds ratio; CI: confidence interval.