Abnormal Gray Matter Volume and Functional Connectivity in Parkinson’s Disease with Rapid Eye Movement Sleep Behavior Disorder

Table 2

One-way ANOVA of GMV and FC differences among PD-RBD, PD-nRBD, and HCs groups.

Brain regional	BA	Coordinates MNI			Clusters sizes	Peak F value
		x	y	z
GMV
Right SOG	18, 19	27	−93	21	87	14.42
Cerebellar vermis IV/V	—	3	−48	8	344	18.92
Left amygdala, extending to bilateral CN, bilateral putamen	36	−18	0	−15	838	31.83
Right angular	39	36	−66	51	368	16.99
Right insula	13	39	24	−3	60	12.33
right cerebellum lobule VI	—	27	−72	−18	124	10.28
Left MCG	6, 24	0	−6	45	93	15.79
FC of right SOG
Left FG	37	−33	−75	−15	51	11.03
Left CS	17	−12	−90	0	237	13.03
Left SPG	7	−30	−60	51	48	9.02
Right SPG	7	36	−60	57	29	10.62
Right MCG	30	0	−15	48	23	10.46
Left cerebellum crus II	—	−21	−91	−33	32	12.55

The significance level of GMV was set at cluster-level corrected with AlphaSim correction with voxel-level value <0.001. BA, Brodmann’s area; MNI, Montreal Neurological Institute; SOG, superior occipital gyrus; CN, caudate nucleus; MCG, middle cingulate gyrus; FG: fusiform gyrus; LG, lingual gyrus; CS, calcarine sulcus; SPG, superior parietal gyrus.