Central Aortic Pressure and Arterial Stiffness in Parkinson’s Disease: A Comparative Study

Table 3

Hemodynamic data according to disease severity and duration in PD patients.

	H&Y < 3		H&Y ≥ 3		-value	-value
	Before LD	After LD	Before LD	After LD
SBP (mm·Hg)	148.54 ± 24.55	139.07 ± 18.95	154.90 ± 37.31	137.32 ± 19.14	≤0.001	≤0.001
DBP (mm·Hg)	83.92 ± 13.70	77.47 ± 13.93	90.97 ± 22.47	77.70 ± 13.14	0.01	0.01
PP (mm·Hg)	64.61 ± 14.65	61.83 ± 13.29	64.12 ± 19.64	59.62 ± 12.37	≤0.001	0.02
HR (minute)	75.35 ± 12.36	78.69 ± 12.74	78.95 ± 12.93	78.92 ± 12.81	0.03	NS
AI (%)	−14.63 ± 28.58	−22.33 ± 20.71	−12.99 ± 29.25	−20.83 ± 30.18	0.01	0.01
CAP (mm·Hg)	149.84 ± 32.73	130.18 ± 19.72	147.08 ± 30.55	128.99 ± 21.92	≤0.001	≤0.001
	DD ≤ 5		DD > 5		-value	-value
	Before LD	After LD	Before LD	After LD
SBP (mm·Hg)	148.21 ± 21.13	136.40 ± 18.16	154.46 ± 37.83	139.71 ± 19.64	≤0.001	≤0.001
DBP (mm·Hg)	85.29 ± 12.79	77.24 ± 12.17	89.06 ± 22.46	77.86 ± 14.57	0.02	≤0.001
PP (mm·Hg)	62.91 ± 13.58	59.43 ± 14.13	65.57 ± 19.69	61.84 ± 11.68	≤0.001	0.01
HR (minute)	75.37 ± 12.78	77.72 ± 12.13	78.53 ± 12.59	79.68 ± 13.22	NS	NS
AI (%)	−14.12 ± 29.59	−20.22 ± 22.16	−13.59 ± 28.36	−22.73 ± 28.34	0.02	0,01
CAP (mm·Hg)	147.68 ± 29.14	129.41 ± 17.11	149.16 ± 33.67	129.75 ± 23.44	≤0.001	≤0.001

AI : augmentation index; CAP : central aortic pressure; DBP : diastolic blood pressure; DD : disease duration; HR : heart rate; H&Y : Hoehn and Yahr score; LD :  levodopa; NS: nonsignificant; PP: pulse pressure; SBP : systolic blood pressure; p₁: H&Y < 3 before and after LD intake; p₂: H&Y ≥ 3 before and after LD intake; p₃: DD ≤ 5 before and after LD intake; p₄: DD > 5 before and after LD intake; NS: nonsignificant. Bold numbers indicate significance.