Research Article

Semaglutide Protects against 6-OHDA Toxicity by Enhancing Autophagy and Inhibiting Oxidative Stress

Figure 4

Changes in the ΔΨm levels in SH-SY5Y cells. (a) Detection of the percentage of green fluorescence of JC-1 by flow cytometry. Green fluorescence indicates a low mitochondrial membrane potential (ΔΨm). (b) The green fluorescence of JC-1 was upregulated in the 6-OHDA group ( vs. the control group). Semaglutide and liraglutide normalized the green fluorescence of JC-1 ( vs. 6-OHDA group) and semaglutide was significantly more effective ( vs. 6-OHDA + liraglutide group). All data were expressed as mean ± standard deviation (n = 4).
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