Protective Role of AMPK against PINK1B9 Flies’ Neurodegeneration with Improved Mitochondrial Function

<div>AMPK alteration in MHC-Gal4 system PINK1B9 flies. (a) Relative AMPK mRNA expression in each group (n ≥ 5/group) tested by RT-PCR. (b–d) p-AMPK-α and AMPK-α protein expression detected by WB in each group (n ≥ 10/group). β-Actin was used as loading control. (e, f) p-ULK1 protein expression detected by WB in each group (n ≥ 10/group). α-Tubulin was used as loading control. Values were expressed as mean ± S.D. 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Parkinson’s Disease

fig1

Figure 1

Figure 1: Protective Role of AMPK against PINK1B9 Flies’ Neurodegeneration with Improved Mitochondrial Function