Sex Differences in the Allele Distribution of PGLYRP2 Variant rs892145 in Parkinson’s Disease
Table 2
Results from the genetic analysis.
Gene
SNP
Allele
Control % (n)
PD % (n)
OR (95% CI)
value
PGLYRP2
rs892145
A
63.2 (733)
62.6 (617)
1.01 (0.85–1.21)
0.96
T
36.8 (427)
37.4 (369)
Female strata
A
61.2 (382)
67.9 (250)
0.76 (0.58–0.99)
0.04
T
38.8 (242)
32.1 (118)
Male strata
A
65.2 (347)
59.4 (367)
1.29 (1.01–1.64)
0.04
T
34.7 (185)
40.7 (251)
rs959117
T
51.4 (588)
50.2 (494)
1.05 (0.88–1.24)
0.61
C
48.6 (556)
49.7 (490)
PGLYRP4
rs10888557
G
90.9 (918)
91.2 (598)
1.01 (0.71–1.43)
0.96
C
9.1 (92)
8.8 (58)
SNP: single nucleotide polymorphism, n: number of alleles, PD: Parkinson’s disease, OR: odds ratio, CI: confidence interval. Data were analyzed with logistic regression with sex as a covariate for the entire cohort and stratified by sex as indicated for rs892145.