Efficacy and Feasibility of Remote Cognitive Remediation Therapy in Parkinson’s Disease: A Randomized Controlled Trial
Table 3
Comparison of mean outcome measure score changes between intervention and control groups.
Variable
p value
Intervention (n = 11)
p value
Control (n = 10)
p value
p value
Pre/Pre
Pre-session
Post-session
I Pre/Post
Pre-session
Post-session
C Pre/Post
Post/Post
RBANS
Total
0.71
98.1 (89.8, 106.4)
96.0 (87.5, 104.5)
0.65
99.4 (90.6, 108.1)
93.5 (84.6, 102.4)
0.05
0.65
Immediate memory
0.42
100.2 (93.8, 106.7)
95.5 (89.0, 102.0)
0.35
93.8 (87.0, 100.6)
93.4 (86.6, 100.3)
0.95
0.95
Visuospatial/construction
0.99
101.2 (89.9, 112.4)
104.0 (91.4, 116.5)
0.96
109.0 (97.2,120.9)
106.9 (93.8, 120.1)
0.98
0.99
Language
0.95
94.8 (85.1, 104.5)
96.7 (89.4, 104.1)
0.95
96.3 (86.1, 106.6)
91.5 (83.8, 99.3)
0.06
0.46
Attention
0.84
101.2 (91.4, 110.9)
97.8 (87.5, 108.1)
0.58
100.5 (90.3, 110.8)
95.2 (84.3, 106.0)
0.79
0.84
Delayed memory
0.88
94.5 (85.4, 103.6)
90.2 (80.8, 99.5)
0.33
99.7 (90.0, 109.3)
90.9 (81.1, 100.7)
0.010
0.88
PDQ-39
Total
0.99
18.5 (10.1, 26.8)
19.0 (10.7, 27.4)
0.99
18.4 (9.6, 27.2)
22.1 (13.4, 30.9)
0.22
0.88
Mobility
0.99
17.0 (7.0, 27.0)
17.8 (5.6, 29.9)
0.99
14.6 (4.0, 25.1)
17.2 (4.4, 30.0)
0.53
0.99
ADL
0.78
11.0 (1.5, 20.5)
14.1 (3.9, 24.3)
0.41
18.7 (8.7, 28.7)
19.1 (8.3, 29.8)
0.75
0.79
Emotional well-being
0.88
21.6 (9.3, 33.8)
20.1 (9.2, 31.0)
0.88
23.2 (10.3, 36.1)
27.3 (15.8, 38.7)
0.76
0.76
Stigma
0.97
12.9 (0.0, 26.2)
16.1 (0.0, 32.8)
0.97
22.7 (8.6, 36.7)
26.1 (8.4, 43.7)
0.78
0.94
Social support
0.43
16.0 (6.6, 25.4)
11.4 (2.2, 20.6)
0.57
4.9 (0.0, 14.8)
11.7 (2.0, 21.3)
0.56
0.99
Cognition
0.99
24.6 (13.0, 36.1)
26.8 (15.1, 38.6)
0.99
23.0 (10.8, 35.1)
32.3 (20.0, 44.7)
0.011
0.57
Communication
0.96
12.4 (0.1, 24.6)
15.0 (3.3, 26.7)
0.83
11.4 (0.0, 24.3)
14.3 (2.0, 26.7)
0.96
0.96
Bodily discomfort
0.95
32.5 (19.6, 45.5)
31.0 (18.2, 43.8)
0.95
28.4 (14.8, 42.0)
29.3 (15.8, 42.8)
0.96
0.96
Reported are the MoCA-adjusted means (95% CI). Reported values are the results of running generalized estimating equation for the pairwise comparisons among pre-intervention, post-intervention, pre-control, and post-control, controlling for MoCA, with the sequential Sidak method for multiplicity correction. pre/pre, pre-intervention vs. pre-control (baseline). I pre/post, pre-intervention vs. post-intervention. C pre/post, pre-control vs. post-control. post/post, post-intervention vs. post-control. ADL, activities of daily living.
