Dyrk1a Phosphorylation of α-Synuclein Mediating Apoptosis of Dopaminergic Neurons in Parkinson’s Disease

Figure 3

(a): HE staining of the brain tissue of mice in each group (×200); (b) immunohistochemical staining; (c) ultrastructural alterations in the nigrostriatal cells of the mouse midbrain; and (d) detection of Dyrk1a and DAT expression by qRT-PCR, :  < 0.05, :  < 0.01, and :  < 0.001 vs. the control group. ^#:  < 0.05, ^##:  < 0.01, and ^###:  < 0.001 vs. the MPTP group.

(a)

(b)

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