Hypoglycemia Awareness Trajectories in Young People with Type 1 Diabetes Using Flash Glucose Monitoring

Table 3

Adjusted logistic regression analysis of trajectory 3 (toward IAH) predictors.

	Univariate analysis		Multivariate analysis^†
	Odds ratio (95% CI)	p-Value	Odds ratio (95% CI)	p-Value
Age	0.920 (0.827, 1.024)	0.126
Gender (male)	0.827 (0.416, 1.643)	0.588
Age at diagnosis	0.927 (0.838, 1.025)	0.137
Gold score	2.252 (1.640, 3.091)	<0.001	2.432 (1.654, 3.575)	<0.001
Insulin regimen	5.333 (0.257, 11.797)	0.279
Diabetes duration	1.008 (0.906, 1.122)	0.884
HbA1c level	0.918 (0.681, 1.237)	0.574
C-peptide negativity	3.200 (1.174, 8.725)	0.023	3.538 (1.170, 10.700)	0.042
Severe hypoglycemia	2.657 (1.651, 4.214)	0.022	2.815 (1.750, 4.982)	0.039
Number of scans	1.041 (0.968, 1.118)	0.277
Percentage of time spent in the target range	1.013 (0.985, 1.042)	0.372
Percentage of time spent below 70 mg/dL	1.004 (0.955, 1.055)	0.881
Percentage of time spent below 54 mg/dL	0.997 (0.941, 1.057)	0.927
Coefficient of variation	0.989 (0.948, 1.031)	0.589
LBGI	1.018 (0.873, 1.186)	0.825

^†Binomial logistic regression model: χ² = 52.662, df = 3, ; Nagelkerke R² = 39.3%; correctly classified cases = 83%. Abbreviations: CI, confidence interval; HbA1c, hemoglobin A1c; LBGI, low blood glucose index; IAH, impaired awareness of hypoglycemia. Results in bold values are considered as statistically significant.