Incidence Trends of Type 2 Diabetes Mellitus, Medication-Induced Diabetes, and Monogenic Diabetes in Canadian Children, Then (2006–2008) and Now (2017–2019)

Table 4

Comparison of clinical characteristics of monogenic diabetes and medication-induced diabetes at presentation in Cohorts 1 and 2.

	Monogenic diabetes		Medication-induced diabetes
	Cohort 1 2006–2008 (N = 30)	Cohort 2 2017–2019 (N = 30)	Cohort 1 2006–2008 (N = 55)	Cohort 2 2017–2019 (N = 52)
Median age (IQR)	11.75 (0, 17.75)	10.85 (8.01, 13.11)	14.58 (3.67, 17.83)]	13.95 (11.68, 16.35)
Female (%)	17 (56.7)	13 (43.0)	30 (54.5%)	22 (42.0)
Hemoglobin A1c
Mean (SD)	7.4 (2.4)	7.4 (1.8)	6.6 (1.9)	7.2 (2.0)
Median (IQR)	6.7 (4.4, 15)	6.7 (5.9, 13.0)	5.9 (4.8, 12.7)	6.7 (4.9, 14.0)
Median BMI (IQR)	18.1 (8.87, 27.4)	19.3 (15.5, 23.4)	22.7 (11.1, 39.8)	20.8 (18.2, 24.3)
Median BMI z-score	0.30 (−1.42, 0.96)	0.65 (−0.31, 1.40)	1.05 (0.02, 2.64)	0.62 (−0.35, 1.83)