Research Article

Glycated Hemoglobin is a Significant Predictor of Femoral, but Not of Carotid or Popliteal, Intima-Media Thickness in Adolescents with Type 1 Diabetes: A Case-Series Study

Table 4

Cardiac and vascular parameters measured by DynaPulse in adolescents with type 1 diabetes by the HbA1c levels.

CharacteristicsHbA1c (%)-value for trend
≤77< and ≤10>10
n = 63n = 180n = 43

Systolic BP (mmHg)96 ± 18104 ± 11103 ± 90.0001
Diastolic BP (mmHg)59 ± 1263 ± 863 ± 70.0006
Central systolic BP (mmHg)112 ± 10115 ± 11115 ± 110.0047
Central diastolic BP (mmHg)66 ± 769 ± 768 ± 70.5575
Mean artery pressure (mmHg)73 ± 977 ± 876 ± 70.0037
Pulse pressure (mmHg)50 ± 1051 ± 951 ± 90.1568
Heart rate (beats/min)77 ± 1479 ± 1285 ± 80.0403
LV ejection time (s)0.26 ± 0.070.27 ± 0.050.26 ± 0.030.0005
LV d/dt max (mmHg/s)1159 ± 2081206 ± 1901213 ± 1970.0006
LV contractility (1/s)16.94 ± 3.4417.59 ± 2.0518.10 ± 1.540.1238
Cardiac output (L/min)4.44 ± 1.344.84 ± 1.065.30 ± 0.950.0548
Cardiac index (L/min/m2)3.10 ± 0.843.32 ± 0.643.61 ± 0.490.3617
Stroke volume (mL)58 ± 1661 ± 1162 (11)0.0459
Stroke volume index (mL/m2)40 ± 842 ± 542 ± 40.9213
Systemic vascular compliance (mL/mmHg)1.18 ± 0.301.23 ± 0.241.25 ± 0.200.6314
Systemic vascular resistance (dynes/s/cm5)1230 ± 3191275 ± 2261177 ± 1670.0947
Brachial artery compliance (mL/mmHg)0.05 ± 0.020.06 ± 0.020.05 ± 0.020.0172
Brachial artery distensibility (%/mmHg)7.02 ± 1.956.80 ± 1.436.90 ± 1.470.2464
Brachial artery resistance (kdynes/s/cm5)284 ± 106275 ± 120263 ± 1220.6632

Data are presented as means ± SDs. LV, left ventricle.