Glycated Hemoglobin is a Significant Predictor of Femoral, but Not of Carotid or Popliteal, Intima-Media Thickness in Adolescents with Type 1 Diabetes: A Case-Series Study
Table 4
Cardiac and vascular parameters measured by DynaPulse in adolescents with type 1 diabetes by the HbA1c levels.
Characteristics
HbA1c (%)
-value for trend
≤7
7< and ≤10
>10
n = 63
n = 180
n = 43
Systolic BP (mmHg)
96 ± 18
104 ± 11
103 ± 9
0.0001
Diastolic BP (mmHg)
59 ± 12
63 ± 8
63 ± 7
0.0006
Central systolic BP (mmHg)
112 ± 10
115 ± 11
115 ± 11
0.0047
Central diastolic BP (mmHg)
66 ± 7
69 ± 7
68 ± 7
0.5575
Mean artery pressure (mmHg)
73 ± 9
77 ± 8
76 ± 7
0.0037
Pulse pressure (mmHg)
50 ± 10
51 ± 9
51 ± 9
0.1568
Heart rate (beats/min)
77 ± 14
79 ± 12
85 ± 8
0.0403
LV ejection time (s)
0.26 ± 0.07
0.27 ± 0.05
0.26 ± 0.03
0.0005
LV d/dt max (mmHg/s)
1159 ± 208
1206 ± 190
1213 ± 197
0.0006
LV contractility (1/s)
16.94 ± 3.44
17.59 ± 2.05
18.10 ± 1.54
0.1238
Cardiac output (L/min)
4.44 ± 1.34
4.84 ± 1.06
5.30 ± 0.95
0.0548
Cardiac index (L/min/m2)
3.10 ± 0.84
3.32 ± 0.64
3.61 ± 0.49
0.3617
Stroke volume (mL)
58 ± 16
61 ± 11
62 (11)
0.0459
Stroke volume index (mL/m2)
40 ± 8
42 ± 5
42 ± 4
0.9213
Systemic vascular compliance (mL/mmHg)
1.18 ± 0.30
1.23 ± 0.24
1.25 ± 0.20
0.6314
Systemic vascular resistance (dynes/s/cm5)
1230 ± 319
1275 ± 226
1177 ± 167
0.0947
Brachial artery compliance (mL/mmHg)
0.05 ± 0.02
0.06 ± 0.02
0.05 ± 0.02
0.0172
Brachial artery distensibility (%/mmHg)
7.02 ± 1.95
6.80 ± 1.43
6.90 ± 1.47
0.2464
Brachial artery resistance (kdynes/s/cm5)
284 ± 106
275 ± 120
263 ± 122
0.6632
Data are presented as means ± SDs. LV, left ventricle.