Research Article

Splitting Mealtime Insulin Doses for Mixed Fat and Protein Meals in Children and Adolescents with Type 1 Diabetes Using Multiple Daily Injection Regimen: A Randomized Cross-Over Trial

Table 1

Clinical characteristics of the study participants.

Variables

Gender
Male, n (%)
Female, n (%)
17 (39.5)
26 (60.5)
Age (year), median (IQR)12 (10–13)
Duration of diabetes (years), median (IQR)3 (2–5)
BMI (kg/m2), median (IQR)16.7 (15–18.5)
Insulin-to-carbohydrate ratio (g/unit), median (IQR)10 (7.5–15)
Insulin sensitivity factor (mg/dL per unit), median (IQR)50 (45–80)
Total daily insulin dose (U/kg/day), mean ± SD0.95 ± 0.09
Basal insulin dose (U/kg/day), median (IQR)0.46 (0.43–0.49)
Basal dose to total daily insulin dose percentage (%), mean ± SD47.6 ± 2.6
HbA1c level
mmol/mol, median (IQR)
%, median (IQR)
61.7 (58.5–66.1)
7.8 (7.5–8.2)

BMI, body mass index; hb A1c, glycated hemoglobin; IQR, interquartile range; SD, standard deviation.