Pediatric Diabetes / 2024 / Article / Tab 3 / Research Article
The Reproducibility and Reliability of Insulin Sensitivity and Secretion Indices in Children and Adolescents Table 3 Spearman correlations and ICCs of insulin sensitivity and secretion measures between visits 1 and 2, and p values of the Spearman correlation comparison between overweight/obese vs. normal weight, Black vs. White, male vs. female, pre-midpuberty vs. post-midpubertal children.
Category Measures Overweight/obese vs. normal weight Black vs. White Male vs. female Pre- vs. post-midpuberty OV/OB correlation Normal weight correlation p -ValueOV/OB ICC Normal weight ICC Black correlation White correlation p -ValueBlack ICC White ICC Male correlation Female correlation p -ValueMale ICC Female ICC Pre-midpuberty correlation Post-midpuberty correlation p -ValuePre-midpuberty ICC Post-midpuberty ICC Insulin sensitivity HOMA-IR 0.72 (0.64–0.78) 0.53 (0.34–0.68) 0.03 0.71 (0.63–0.77) 0.50 (0.31–0.65) 0.76 (0.63–0.85) 0.74 (0.66–0.81) 0.83 0.38 (0.15–0.57) 0.82 (0.76–0.87) 0.72 (0.61–0.79) 0.72 (0.63–0.79) 0.91 0.83 (0.76–0.88) 0.66 (0.56–0.74) 0.73 (0.61–0.82) 0.73 (0.65–0.79) 0.97 0.63 (0.48–0.75) 0.79 (0.73–0.84) QUICKI 0.72 (0.64–0.78) 0.53 (0.34–0.68) 0.03 0.73 (0.66–0.79) 0.50 (0.31–0.65) 0.76 (0.63–0.85) 0.74 (0.66–0.81) 0.83 0.67 (0.51–0.78) 0.75 (0.67–0.81) 0.72 (0.61–0.79) 0.72 (0.63–0.79) 0.91 0.73 (0.63–0.80) 0.72 (0.63–0.79) 0.73 (0.61–0.82) 0.73 (0.65–0.79) 0.97 0.70 (0.67–0.80) 0.74 (0.67–0.80) FGIR 0.75 (0.68–0.81) 0.56 (0.40–0.71) 0.02 0.70 (0.62–0.77) 0.48 (0.28–0.64) 0.82 (0.71–0.88) 0.76 (0.68–0.82) 0.33 0.66 (0.50–0.78) 0.68 (0.59–0.76) 0.75 (0.66–0.82) 0.76 (0.68–0.82) 0.89 0.66 (0.54–0.75) 0.67 (0.57–0.75) 0.74 (0.61–0.82) 0.77 (0.70–0.82) 0.59 0.65 (0.50–0.76) 0.69 (0.61–0.76) 1/Fasting insulin 0.75 (0.68–0.81) 0.54 (0.35–0.69) 0.01 0.69 (0.61–0.76) 0.46 (0.26–0.62) 0.80 (0.68–0.87) 0.76 (0.68–0.82) 0.53 0.65 (0.48–0.77) 0.67 (0.57–0.75) 0.74 (0.65–0.79) 0.78 (0.68–0.82) 0.76 0.64 (0.52–0.74) 0.68 (0.58–0.76) 0.75 (0.63–0.83) 0.76 (0.69–0.81) 0.84 0.64 (0.49–0.75) 0.68 (0.59–0.75) WBISI 0.80 (0.74–0.84) 0.83 (0.74–0.89) 0.54 0.75 (0.68–0.81) 0.79 (0.68–0.86) 0.81 (0.70–0.88) 0.86 (0.81–0.89) 0.26 0.78 (0.66–0.86) 0.83 (0.77–0.87) 0.85 (0.78–0.89) 0.81 (0.75–0.86) 0.41 0.81 (0.74–0.86) 0.78 (0.71–0.84) 0.82 (0.73–0.61) 0.84 (0.79–0.88) 0.72 0.84 (0.76–0.89) 0.78 (0.72–0.83) Insulin secretion HOMA-B 0.68 (0.59–0.75) 0.61 (0.44–0.74) 0.43 0.26 (0.12–0.39 0.60 (0.43–0.73) 0.71 (0.56–0.81) 0.68 (0.58–0.75) 0.66 0.26 (0.02–0.47) 0.61 (0.50–0.70) 0.71 (0.60–0.79) 0.66 (0.55–0.74) 0.48 0.72 (0.62–0.80) 0.23 (0.07–0.38) 0.66 (0.52–0.77) 0.70 (0.61–0.76) 0.66 0.24 (0.02–0.44) 0.34 (0.20–0.46) IGI 0.56 (0.45–0.65) 0.65 (0.49–0.77) 0.33 −0.04 (−0.18–0.10) 0.31 (0.09–0.50) 0.55 (0.35–0.70) 0.62 (0.50–0.70) 0.53 −0.07 (−0.31–0.17) 0.22 (0.07 –0.36) 0.67 (0.55–0.76) 0.55 (0.43–0.67) 0.14 0.51 (0.36–0.63) −0.07 (−0.23–0.10) 0.66 (0.51–0.77) 0.59 (0.48–0.68) 0.39 0.36 (0.15–0.54) −0.04 (−0.18 –0.11) DI 0.49 (0.37–0.59) 0.58 (0.40–0.72) 0.36 −0.11 (−0.25–0.03) 0.13 (−0.10 –0.35) 0.49 (0.27–0.65) 0.54 (0.42–0.65) 0.61 −0.12 (−0.35–0.12) 0.04 (−0.12–0.20) 0.64 (0.51–0.73) 0.41 (0.27–0.54) 0.01 0.30 (0.13–0.46) −0.09 (−0.25 –0.08) 0.61 (0.44–0.73) 0.48 (0.36–0.58) 0.19 0.17 (−0.05–0.38) −0.07 (−0.21 –0.08)