Review Article

Type 1 Diabetes and Other Autoimmune Disorders in Children

Figure 1

Summary of the major associations within the HLA class II with autoimmune diseases. Abbreviations. CD, celiac disease; GD, graves disease; HT, hashimoto thyroiditis; IBD, inflammatory bowel diseases; JIA, juvenile idiopathic arthritis; MS, multiple sclerosis; T1D, Type 1 diabetes; NS, nephrotic syndrome (Minimal change disease). Unbroken lines represent the increased susceptibility to the disease having the HLA; broken lines represent the protective effect of HLA on the development of the disease.