The PPARγ Agonist Rosiglitazone Is Antifibrotic for Scleroderma Lung Fibroblasts: Mechanisms of Action and Differential Racial Effects

Figure 3

Rosiglitazone increases PPARγ expression in SSc lung fibroblasts in a time-dependant manner. Lung fibroblasts were incubated with rosiglitazone (20 μM) for time indicated. Cells were collected and subjected to Western analysis for PPARγ expression. Anti-β-actin antibody was used as a loading control. Immunoblots are representative from 3 independent experiments.