Pulmonary Rehabilitation in COPD: A Reappraisal (2008–2012)

Table 1

Selected studies for the review and used outcomes.

Main author/year	Type of study	Outcomes
van Ranst et al. 2011 [23]	Retrospective, observational	(i) Peripheral muscle performance; (ii) Respiratory muscle strength; (iii) Cycle exercise endurance and 6 MWDT; (iv) CRQ, SGRQ, SF-36
Yoshimi et al. 2012 [24]	Prospective, observational	(i) Respiratory muscle strength; (ii) 6 MWDT; (iii) SGRQ
Murphy et al. 2011 [22]	Single-blind cluster randomised trial	(i) 1°: CRQ; (ii) 2°: ISWT, Self-efficacy for Managing Chronic Disease 6-Item Scale
Fischer et al. 2012 [25]	Prospective, observational	(i) 6 MWDT; (ii) Correlation between concerns about exercise and 6 MWDT
Gale et al. 2011 [26]	Prospective cohort study	(i) PWV, BP, IL-6, fasting glucose and lipids; (ii) ISWT
Riario-Sforza et al. 2009 [27]	Number needed to treat study	6 MWDT
Enfield et al. 2010 [28]	Retrospective, observational cohort study	Relationship between 6 MWD and survival
Cheikh Rejbi et al. 2010 [29]	Prospective, observational	6 MWDT and peak oxygen uptake in COPD and healthy subjects
Ergün et al. 2011 [18]	Prospective, observational	(i) MRC, BORG dyspnea scale; (ii) ISWT, ESWT, FEV1; (iii) SGRQ, HADs; (iv) Body composition: BMI, FFM
Scott et al. 2010 [30]	Prospective, observational	(i) Compliance; (ii) SGRQ; (iii) 6 MWDT; (iv) BORG dyspnea scale
Stav et al. 2009 [31]	Matched controlled trial	(i) FEV1; (ii) 6 MWDT; (iii) BMI
Moore et al. 2009 [19]	Randomised pilot study	(i) ISWT; (ii) CRQ
Steele et al. 2008 [32]	Randomised clinical trial	(i) Daily activity with accelerometer; (ii) Exercise adherence with diary; (iii) 6 MWDT
Eaton et al. 2009 [33]	Prospective randomized controlled study	Risk of readmission at 3 months after an exacerbation
Chang et al. 2008 [20]	Three-group randomised controlled trial	(i) 1°: SGRQ; (ii) 2°: FAI, IPAQ, ISWT, FEV1
Elçi et al. 2008 [34]	Randomized, controlled, prospective study	(i) MRC; (ii) 6MWDT; (iii) SF-36; (iv) HADs; (v) SGRQ
Van Wetering et al. 2010 [21]	Randomised controlled trial	(i) 1°: SGRQ, n° of exacerbations; (ii) 2°: subscores of SGRQ, MRC, 6 MWDT, muscle strength, FFM, lung function
Gottlieb et al. 2011 [35]	Single-centre, randomized, placebo-controlled, unblinded clinical trial	(i) 6 MWDT; (ii) Leg strength; (iii) SGRQ
Sabit et al. 2008 [36]	Retrospective case note study	Identifying variables that affect poor attendance to PR programme

6 MWDT: 6-minute walking distance test, CRQ: chronic respiratory disease questionnaire, SGRQ: St George’s respiratory questionnaire, SF-36: medical outcomes study short-form survey, PWV: aortic pulse wave velocity, BP: blood pressure, IL-6: interleukin-6, ISWT: incremental shuttle walk test, ESWT: endurance shuttle walking test, HADs: hospital anxiety depression scale, BMI: body mass index, FFM: fat free mass, FEV₁: forced expiratory volume in one second, FAI: Frenchay activities index, IPAQ: international physical activity questionnaire.