Pediatric COVID-19: Correlations between Clinical and Imaging Perspectives

Table 3

Comparison between the clinical and radiological characteristics of the studied patients with and without comorbidities.

Variables	COVID-19 patients without comorbidities	COVID-19 patients with comorbidities
	Wheezes	18 (45.0%)		32 (80.0%)	<0.001
Respiratory distress	15 (37.5%)	32 (80.0%)	0.001
Respiratory rate,
Range	16–55	16–55	0.008
Cardiac manifestations	6 (15.0%)	22 (55.0%)	0.003
Clinical severity
Mild	9 (22.5%)	3 (7.5%)
Moderate	19 (47.5%)	3 (7.5%)
Severe	10 (25.0%)	18 (45.0%)	<0.001
Critical	2 (5.0%)	16 (40.0%)
Intensive care unit admission	10 (25.0%)	35 (87.5%)	<0.001
Mechanical ventilation	1 (2.5%)	27 (67.5%)	<0.001
Mortality	1 (2.5%)	12 (30.0%)	0.004
COVID-19 severity assessment score
Median (IQR)	3 (0–5)	4 (2–5)	0.212
Range	0–6	0–6
Abnormal radiological findings	16 (40.0%)	29 (72.5%)	0.005
Lesion size and density			0.029
Ground-glass opacities (GGOs)	7 (17.5%)	8 (20.0%)
Consolidation	3 (7.5%)	16 (40.0%)
Ground-glass opacities (GGOs) and consolidation	3 (7.5%)	4 (10.0%)
Bronchiectasis changes	1 (2.5%)	0 (0.0%)
Number of lobes affected			0.018
Median (IQR)	0 (0–3)	3 (0–4)
Range	0–6	0–6
The affected lung sides			0.024
No	26 (65.0%)	9 (22.5%)
Bilateral	10 (25.0%)	26 (65.0%)
Unilateral	4 (10.0%)	5 (12.5%)
RSNA expert consensus statement			0.046
Negative	26 (65.0%)	9 (22.5%)
Indeterminate	10 (25.0%)	14 (35.0%)
Atypical	4 (10.0%)	10 (25.0%)
Typical	0 (0.0%)	7 (17.5%)
Chest X-ray score			0.005
Median (IQR)	0 (0–3)	4 (0–4)
Range	0–6	0–6
RAPID-COVID score			<0.001
Median (IQR)	1 (1–2)	5 (2–6)
Range	1–6	1–8
Chest CT severity score (CT-SS)			0.002
Median (IQR)	0 (0–10)	12 (0–24)
Range	0–32	0–32

RSNA: Radiological Society of North America Expert Consensus Statement. is significant; is highly significant.